In the Pro version of this plugin, you can create as many Option Sets as you like, and set any one of them as active. Using this feature, you can experiment with a new set of options and leave them as active if satisfactory, or revert to your original set if unsatisfactory.
If you enable Mobile Support (another Pro feature), two Option Sets (Phone and Tablet) will be created for you. They will be used when your blog is being viewed on phones and tablets respectively.